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Additional caution or monitoring may be appropriate in research settings involving: Active cancer- or tumor-related research models, where antioxidant-related pathways may influence cellular-response or treatment-response mechanisms Severe asthma or hypersensitivity-prone research models, as rare sensitivity-related observations have been reported in some experimental contexts Sulfur-sensitive research models, due to Glutathione containing a thiol (sulfur-containing) group Complex hepatic-function or detoxification-related investigations, where antioxidant modulation may influence oxidative-stress or liver-related biomarkers Research conditions, research amounts, protocol duration, administration frequency, and concurrent compounds may influence tolerability observations across experimental settings
In addition, it has been debated whether erythrocyte membrane injury could promote the thrombotic complications frequently observed in COVID-19 patients [342], and that reduced deformability of erythrocytes may contribute to inflammation and hypoxia in COVID-19 patients [343]
Reduces cellular degeneration caused by aging and stress
