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Pharmacological treatment approaches include treatment with -blockers, fludrocortisone, midodrine, increase in salt and fluid intake, intravenously administered salt, compression stockings for postural orthostatic tachycardia syndrome (POTS) and even for myalgic encephalomyelitis or chronic fatigue syndrome treatment (248)

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Natural compounds are used widely in the treatment of various cancers, including RCC (174)

TMAO is associated with mortality: Impact of modestly impaired renal function