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Isotretinoin products (e.g., Amnesteem, Absorica, Claravis, Myorisan, Zenatane) for acne: typically a 1-month deferral
The safety profile observed in the placebo-controlled trial of dapagliflozin in pediatric patients with type 2 diabetes mellitus was similar to that observed in adults [see Adverse Reactions (6.1)]
In contrast, CNS, but not vagal, GLP-1Rs were required for a complete anorectic response to the long-acting GLP-1R agonist liraglutide and the anorectic and weight loss effects of chronic liraglutide treatment
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This was further supported by Li et al.s work, which indicated that Dula lowered ROS amounts in a model of type II collagen and aggrecan breakdown set on by AGEs in humans (Li et al
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