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[note 18] [232] [198] Transporter internalization via TAAR1's G 13 -coupled pathway is transient because G s -cAMP-PKA signaling functionally inhibits RhoA's downstream activity

This observation suggests that the menopause transition (MT) contributes to an increased risk of heart disease [20, 31]

The thyroid gland is a highly vascular, brownish-red gland located in the visceral compartment of the anterior region of the neck

12, 13, 14, 15 A comprehensive review of the literature (including animal studies) was conducted in August 2015 using PubMed, Embase, and BIOSIS databases, searching for English language articles with no year restrictions, using defined search strategies based on input from five of the cited group members with experience of treating multiple patients with HT-1

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