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Your doctor should review your complete medication profile, but many menopausal women safely use both

Gastrointestinal effects: Retatrutide, like other GLP-1 receptor agonists, commonly causes nausea, vomiting, and reduced appetite, as documented in the SmPCs for licensed GLP-1-based medicines such as semaglutide and tirzepatide

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Lastly, keep in mind that most studies showing efficacy of GLP-1 agonists for weight loss usually require participants to make lifestyle modifications such as changes in diet and exercise, to control portions and eat high nutrient, low energy foods and move more while taking the medications