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Pfeiffer CM, Huff DL, Gunter EW: Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory setting

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74 In one randomized, placebo-controlled, crossover trial that included 24 healthy participants aged 55 years and older who had no major sleep issues, 5 mg melatonin 30 minutes before bedtime in controlled experimental conditions increased sleep efficiency, mainly by increasing stage 2 NREM sleep and slightly shortening awakenings

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