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Sex-related Response Patterns To Semaglutide Understanding the impact of patient sex on treatment response is critical to optimising obesity therapies [55]

Semaglutide is primarily metabolized through proteolytic cleavage (protein breakdown) and beta-oxidation of the fatty acid side chain

According to FDA prescribing information, semaglutide is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Semaglutide belong to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists which are approved by the FDA for adults with obesity or type 2 diabetes

Typically, it's prescribed for adults with a body mass index (BMI) of 30 kg/m or greater, or a BMI of 27 kg/m or greater with at least one weight-related condition (like high blood pressure, type 2 diabetes, or high cholesterol)