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In the STEP trials for semaglutide and the SURMOUNT trials for tirzepatide, participants achieved substantial weight loss that far exceeded what most people accomplish through diet and exercise alone

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They've got a total of 2 ingredients in common

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Ethical approval All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5)