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Summary Keywords glutathione metabolism, hippocampal injury, multi-omics, oxidative stress, sepsis-associated encephalopathy Citation Li Y, Wang L, Ma T, Peng T, Wang L, Wang J, Li Y and Wang Y (2026) Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis-associated encephalopathy: an integrated proteomics and metabolomics study