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Gareau et al., 2011

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Therefore, the inverse relationship between BMI and osteocalcin levels could indicate that only healthy adipose tissue may be involved in osteocalcin production (233)

However, exenatide is considered the most efficient in crossing the BBB based on its rate of brain influx, its percentage reaching the brain that accumulates in the brain parenchyma, and the percentage of the systemic dose taken up per gram of brain tissue [18]