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Outlier removal Mouse and rat samples were subjected to vsd-transformation using DESeq2 v1.30.1 followed by PCA

To evaluate the biological events activated in tendons with tendinopathy, we performed enrichment analysis of the hallmark gene sets of the top 100 upregulated genes in tendons with tendinopathy

These Phase 3 trials enrolled thousands of participants across multiple studies, providing robust evidence for efficacy and safety