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Journal of Nutrition 2004;20:709-715

DPP-4 inhibitors can also be combined with an insulin therapy

IGF-1 elevation is the primary mechanism through which full HGH increases the risk of insulin resistance, fluid retention, and certain growth-related effects at high doses

Apart from IL-6, there are other drivers that involve the same pathway for induction of PC via inflammation, which includes IL-11, IL-8, Oncostatin M (OSM), and Leukemia inhibitory factor (LIF)