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Resveratrol as a therapeutic agent for Alzheimers disease
Contact your GP if you experience: Significant weakness affecting daily activities (difficulty climbing stairs, rising from chairs, carrying shopping) Rapid or excessive weight loss (more than 1 kg per week consistently after the initial 2-4 weeks) Difficulty consuming adequate protein due to persistent nausea or vomiting Noticeable muscle wasting , particularly in the arms, legs, or shoulders Falls or balance problems that may indicate reduced muscle strength Fatigue or exhaustion disproportionate to your activity level Concerns about nutritional adequacy or inability to maintain a balanced diet Seek urgent medical care if you develop: Severe, persistent abdominal pain (especially if accompanied by vomiting) Jaundice (yellowing of skin/eyes), pale stools, or dark urine Inability to keep fluids down for more than 24 hours Reduced urine output, dizziness, or signs of dehydration Your GP may consider several investigations and interventions: Body composition assessment where available, or functional measures like grip strength and chair stand tests Blood tests including full blood count, renal function, liver function, thyroid function, vitamin D levels, and HbA1c (for diabetes monitoring) Review of medication dosing sometimes reducing the semaglutide dose or slowing titration can improve tolerability Referral to a dietitian for specialised nutritional support and meal planning Referral to physiotherapy or exercise programmes for supervised resistance training Assessment for sarcopenia in older adults using validated screening tools such as SARC-F Treatment adjustments may be necessary if muscle loss is excessive or causing functional impairment
Consensus Clinical Guide, June 2024
95% CI, 0.08-0.62)
