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The most realistic approach for most people: use the keto plus GLP-1 combination during the active weight loss phase (typically 6 to 18 months), then transition to either maintained keto as a GLP-1 exit strategy, continued GLP-1 at a maintenance dose with a more moderate low-carb diet, or a gradual return to a protein-prioritized diet that may include more carbohydrates than strict keto while maintaining the metabolic awareness and habits built during the keto phase

Another difference between the two tissues pertains to the early postnatal profile of GST activity, which at birth, is immature in the liver and at its maximal level in choroid plexuses [11]

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Annals of Hepatology, 2021

Wegovy mimics the action of GLP-1 and helps your body stay satiated by controlling appetite and reducing cravings