As sulfur amino acid input rises, so does glutathione concentration but not as fast as it would if the inhibition were not present
The quantity of GSH can also be determined by subtracting the amount of GSSG from the total amount of glutathione
fermentum A51 were annotated by CAZy, including auxiliary oxidoreductases (AAs, 3 genes), carbohydrate esterases (CEs, 9 genes), functional domains of carbohydrate-binding modules (CBMs, 9 genes), glycoside hydrolases (GHs, 17 genes) and glycosyltransferases (GTs, 13 genes) (Figures 4A,B)
Pathway analysis of siGSTO1 Bru-Seq data was also performed using IPA (Ingenuity Systems, Inc., Redwood City, CA) with genes showing fold change 2
10.1074/jbc.M110.184176 J