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Mechanism of Action Mitochondrial Electron Transport : R-lipoic acid functions as a critical coenzyme in the mitochondrial electron transport chain, facilitating the conversion of pyruvate to acetyl-CoA and supporting efficient ATP synthesis for cellular health

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It is secreted following nutrient ingestion, resulting in enhanced glucose-stimulated insulin secretion (GSIS) from the pancreatic -cells as well as delayed gastric emptying and enhanced satiety, making it an attractive target for the treatment of T2D and obesity 3

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Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3