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5.9 Risk of Seizures with Abrupt Withdrawal of QSYMIA Abrupt withdrawal of topiramate has been associated with seizures in individuals without a history of seizures or epilepsy

In a study of 50 men (ages 17 to 32 years) receiving Accutanetherapy for nodular acne, no significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology or seminal plasma fructose