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Inflammation One pathway involved in TMAO-induced inflammation is the activation of protein kinase C (PKC) and NF-kB, increasing the expression of cell adhesion molecules such as VCAM1 and ICAM1, facilitating monocyte recruitment into the vessel wall, and increasing atherogenesis

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Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation