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Quick Answer: GHRP-2, GHRP-6, hexarelin, and ipamorelin are all synthetic GHS-R1a agonists that stimulate pulsatile growth hormone secretion, but they differ substantially in potency, receptor selectivity, cortisol co-stimulation, and secondary tissue effects differences that determine which compound researchers select for a given model

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Suppresses Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation and IL-1 release through AMPK-dependent autophagy in a HFD-induced IR mice model, countering palmitate-induced inflammation [180]

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