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However, the reverse reaction of Michael addition is underutilized

Only micro amounts of beta-alanine make their way to the bloodstream

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Its used for pernicious anemia, malabsorption syndromes, and certain neurological disorders linked to B12 deficiency

By in-licensing early in development, Merck has an opportunity to optimize, and control, the development AND the manufacturing process in the early development phase of the asset, thus reducing risk (and potentially costs) by virtue of not having to transfer manufacturing processes, repeat studies, etc