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Some people have more sensitive digestive systems, while others have different metabolic rates

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Strengths of this study include the large sample size comprising men and women, the demographically homogeneous group of Italians from European ancestry, the exclusion of confounding chronic disorders potentially affecting both UA and inflammatory biomarkers, the clinical and laboratory variables collected by trained professionals in a standardized manner, and maintained in a constantly updated database with a low rate of missing data, the centralization of laboratory analyses, the inclusion of several well-validated inflammatory biomarkers, and the use of OGTT and HbA1c data to carefully diagnose diabetes mellitus