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Most injection-site reactions are limited to mild redness or swelling that fades within hours

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Its worth noting that fatigue is also a common side effect of Wegovy, particularly in the first few weeks of treatment as you adjust to each dose increase

Tirzepatide, by contrast, activates both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptors simultaneously, producing rapid satiety signaling, improved insulin sensitivity, and accelerated weight reduction

An analysis of 26 studies (total 3020 patients) including 5 studies with psychiatric symptoms assessed as primary outcomes (for example, substance use disorders), and 21 studies with secondary outcomes, as well as an additional 10 registered clinical studies, was performed