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In STEP 1 (NEJM 2021), FDA-approved semaglutide 2.4 mg with lifestyle support produced a mean 14.9% body weight reduction at 68 weeks versus 2.4% with placebo

GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed type 2 diabetes and weight management

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