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Always discuss potential benefits and risks with your doctor before starting treatment
Extra caution may be needed with medicines that have a narrow therapeutic index, such as warfarin or digoxin , especially when starting treatment or increasing the dose
Handling of dropouts or missing data For the efficacy endpoints, the last observation carried forward method was used for missing data imputation
Before testing, all sera were pre-treated with disodium EDTA (final concentration 10 mM, pH 7.4) (Sigma-Aldrich, Milan, Italy), in order to rule out underestimation of antibody MFI strength due to the prozone phenomenon
Consult an expert prior to initiating any peptide protocol
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