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Kratz F, Drevs J, Bing G, Stockmar C, Scheuermann K, Lazar P, Unger C: Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates

Kidney Issues GLP-1 drugs can sometimes impact kidney function, manifesting as: Dehydration, often due to nausea and vomiting Changes in urination patterns Swelling in the legs or ankles Patients with pre-existing kidney conditions should discuss GLP-1 treatments with their healthcare provider to assess potential risks

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Overall the full-length preproproteins are 75% conserved across various vertebrate species