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Consequently, compensatory activated collateral blood vessels and reorganized blood flow following BPC 157 treatment in rats with the occluded major peripheral vessel(s) or central vessels reduced superior sagittal sinus, portal and caval hypertension, aortal hypotension, progressive venous and arterial thrombosis peripherally and centrally, and ECG disturbances

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Discovery and Characterization SLU-PP-332 was identified through medicinal chemistry efforts at Saint Louis University (hence "SLU" in the name) to develop selective ERR modulators

While more large-scale human studies are needed, current research and clinical use suggest that BPC-157 is well tolerated and low-risk when used under medical supervision