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doi:10.31557/APJCP.2021.22.2.457 67 Ayush O, Jin ZW, Kim HK, Shin YR, Im SY, Lee HK

When photosynthetic capacity is overwhelmed, chloroplasts produce elevated levels of ROS, particularly 1 O 2 , leading to lipid peroxidation, chloroplast damage, and irreversible photoinhibition ( Plants have evolved photoprotective mechanisms, including non-photochemical quenching (NPQ) and enzymatic ROS scavenging

Rather than alterations in single components, the impact on depression pathobiology may be due to the net effect of different dysregulations and interrelated compensatory mechanisms in such a complex network, which could be fully unraveled only by further functional and mechanistic studies

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