Medication can cause mild dehydration, compounding effects of Houstons climate on fluid balance throughout Space City
In fact, weight loss from semaglutide often improves irregular periods caused by polycystic ovary syndrome (PCOS) or metabolic dysfunction
Two caveats are important
A 2024 study published in , reported by Verywell Health, found a JAMA Ophthalmology four times higher risk of NAION in diabetic patients taking semaglutide, and a seven times higher risk among obese patients
Choosing Between Semaglutide and Tirzepatide for Microdosing From a pharmacology standpoint, semaglutide is a pure GLP-1 receptor agonist , while tirzepatide is a dual GIP/GLP-1 agonist that activates both GIP and GLP-1 receptors.[2,4] That dual mechanism likely contributes to tirzepatides strong weight-loss results at full doses compared with semaglutide in head-to-head and indirect comparisons.[2,7] In the context of microdosing: Some clinicians and patients feel that microdosing tirzepatide provides robust appetite control even at relatively low doses, though this is based largely on real-world experience rather than large trials
