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GLP-1 receptor agonists carry a boxed warning regarding thyroid C-cell tumors observed in animal studies, and while the relevance to humans remains uncertain, patients with personal or family history of medullary thyroid carcinoma should not use these medications

Endogenously, GLP-1 is a hormone produced primarily by the enteroendocrine cells of the intestinal wall in response to food intake

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Instead, it works as a digestive passenger with remarkable benefits along the way