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Further, these studies have concurrently indicated that the increase of the serum selenium status leads to the corresponding increase of plasma GPx level up to a threshold and beyond that GPx activity is saturated with no further increase irrespective of the selenium status

Antisense oligonucleotides (ASOs) are short single-stranded DNA or RNA molecules (or chemical analogs) that bind and induce the degradation of target RNAs

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2d), which can ensure the entire filling of the defect and maintain an appropriate microenvironment for cartilage regeneration 35