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For example, pathways involved in glutathione metabolism or GCLC regulation might also be modified in the cases, which would affect the sensitivity of PDX tumors to BSO

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Furthermore, the time-to-onset and severe outcomes of GLP-1 RAs-induced gastrointestinal AEs were also discussed, which was helpful for clinical practice and drug monitoring to a certain extent

In one study, participants regained two-thirds of their previous weight loss within the year after stopping the medication