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[DOI] [PMC free article] [PubMed] [Google Scholar] 796.Todaro M, et al

Supplied as a freeze-dried (lyophilized) porous white solid and must be reconstituted with sterile water for injection or normal saline before administration

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oxidation of iodide, iodination of tyrosine residues of thyroglobulin (Tg), and the oxidative coupling of iodinated tyrosine residues to generate Tg-bound TH, are catalyzed by the enzyme thyroid peroxidase (TPO), which is located in the apical membrane of the thyrocyte generating hydrogen peroxide (H2O2) as a substrate [61, 62]