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not therapeutic claims.) Dual GLP-1R/GCGR receptor activation profile studied in published Phase 2 and Phase 3 trials (GLORY program, DREAMS program)

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(iv) the 2-oxoadipate dehydrogenase complex that catalyzes the decarboxylation of 2-oxoadipate to glutaryl-CoA in the catabolic pathway of lysine, hydroxylysine, and tryptophan