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Medical Conditions to Inform Your Doctor Dosing and Use Precautions Use exactly as prescribed (0.25 mg to 2.4 mg titration schedule) Administer once weekly on the same day each week Do not increase or skip doses without medical advice Rotate injection sites (abdomen, thigh, or upper arm) Gastrointestinal Effects Nausea, vomiting, or diarrhea are common during dose escalation Eat small, low-fat meals to reduce discomfort Maintain adequate hydration to avoid dehydration Hypoglycemia Risk Increased risk when used with insulin or sulfonylureas Monitor blood sugar regularly if combined with diabetes medicines Pregnancy and Breastfeeding Not recommended during pregnancy Should be avoided during breastfeeding unless prescribed General Advice Do not stop treatment suddenly without medical guidance Store as per instructions (usually refrigerated) Inform your doctor about all medications you are taking Regular monitoring of weight and metabolic health is recommended Usage The effective use of the Wegovy FlexTouch Pre-filled Pen depends on a consistent weekly schedule and a gradual dose escalation to ensure the best results while allowing the body to adapt

For more detailed guidance, see our guide on what to eat while on Mounjaro

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doi: 10.1093/cvr/cvac120