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Description GHK-Cu (Glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide-copper(II) complex first isolated from human plasma by Pickart in 1973

We recommend starting with a dosage of two to four IU

This lack of significant improvement may be attributed to the activation of VEGF-independent angiogenic pathways, the recruitment of proangiogenic stromal cells, the induction of vasculogenesis or even the dose of the antiangiogenic agent used, which may reduce the size of blood vessel pores, further obstructing the delivery of this antibody [30, 39, 40]

doi: 10.1186/s12887-021-02816-8

Ikonomidou C, Kaindl AM