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This approach is not appropriate for individuals with opioid use disorder or acute liver disease

The GR signaling pathway associated with carriage of the G allele of the rs2270777 CDK4 SNP showing increased GR co-regulator activity (e.g., NCOA3 , DRIP205 , SMARCA4 and CBP increased expression +1.2-fold) (Table 4, Supplementary Figure S3)

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