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The studies that exist for berberine suggest that you will want to take it for at least 13 weeks, but I would recommend using it for even longer

Common Side Effects: Serious side effects include: heart attack, chest pain, coronary artery disease, exacerbation or new onset of hypertension, new onset heart failure, gastritis, gastric ulcer, gastrointestinal perforation, gastric bleeding, prolonged bleeding, changes in red and white blood cells, liver injury, facial swelling, skin rash, kidney damage, and pulmonary hypertension

If you have not already faced this scenario, there is a good chance that you will someday soon