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Importantly, recent research suggests that paternal preconception interventions, such as dietary restriction or exercise, may restore sperm epigenetic integrity and reduce offspring metabolic risk [103]

To maximise the cardiovascular benefits of GLP-1 RAs at a population level, strategies can be used to improve tolerability, such as patient counselling, gradual dose escalation and the use of long-acting formulations [27]

10.1016/j.chroma.2008.10.024 J

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Antimicrob Agents Chemother 44:31183121