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Mast cells are highly armed defensive system similar to our soldiers and police, protecting the body from outside and inside threats, including invasion of infectious agents, parasites, injuries, and toxins

For example, protein aggregation and amyloid formation occur in NDDs such as AD, PD, and ALS

There are many factors driving the alarming rates of increased surgery ranging from system-level factors such as inadequate reimbursement for physiotherapy treatment to personal-level factors such as individual beliefs and education of patients and their health care providers

Western blot analysis (Fig

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