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This release of histamine and tryptase increases blood flow to the skeletal muscles during exercise.[ref] Hypoxia has also been shown to induce mast cell degranulation.[ref] This is a normal response for most people, and the body can handle a certain increase in histamine and tryptase

Contributes to deep sleep regulation by strengthening natural GH pulse patterns during slow-wave sleep

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Better Tolerance for Sensitive Stomachs Some people find that taking supplements on a completely empty stomach in the morning causes mild digestive discomfort

Antioxidants 8(4):105