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It is well documented that concomitant use of the CYP2E1 inducer isoniazid increases the risk of hepatotoxicity, though whether 2E1 induction is related to the hepatotoxicity in this case is unclear.[40][41] Concomitant use of other drugs that induce CYP enzymes such as antiepileptics (including carbamazepine, phenytoin, and barbiturates) have also been reported as risk factors

In simple terms, it is studied for its ability to signal fat cells to release and burn stored fat while leaving blood sugar regulation largely untouched

Plant Cell 6 , 17131729 (1994)

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