The initial search used a mass tolerance of 20 ppm, while the main search used a mass tolerance of 5 ppm, and the fragment ion mass tolerance was set at 0.02 Da
Further exploration revealed that this was driven mainly by the difference between patients with ME/CFS and HCs (F = 9.589, p = 0.004), with ME/CFS patients showing higher lactate levels than controls, although a trend towards significant difference between patients with ME/CFS and long COVID was also noted (F = 4.031, p = 0.052)
Furthermore, excessive amounts of phospholipase A in seminal plasma can combine with egg yolk to produce toxic substances such as lipid peroxides, which are detrimental to long-term semen preservation [4]
DescriptionBiologically reactive metabolites are known for their ability to bind to nucleophilic macromolecules (DNA, proteins, lipids) and their irreversible binding to hepatic proteins is known to lead to necrosis and liver damage
Important Notes Practical considerations for consistency and safety