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In the 72-week SURMOUNT-5 trial described in this article, average weight reduction was 20.2% with tirzepatide and 13.7% with semaglutide among adults with obesity without type 2 diabetes

With weekly protocols ranging from 0.5ml to 2ml per injection despite containing nearly identical active ingredients

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The Journal of Biological Chemistry, 271 (18), 10577-10582

Avoid strenuous exercise for 24 hours and monitor yourself for unusual fatigue or dizziness