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(1.5) Treatment of moderately to severely active ulcerative colitis in adults and pediatric patients 5 years of age and older

MOTS-c Human Studies: Initiating rigorous human clinical trials for MOTS-c to validate its preclinical findings and establish its safety and efficacy

Prior to starting immunosuppressive therapy, screening for infections such as tuberculosis and hepatitis is standard practice

The activation of Wnt/-catenin pathway can promote the proliferation and differentiation of mesenchymal stem cells and osteoblasts, increase cell activity and promote osteogenic differentiation (Wu et al., 2017) (Figure 1)

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