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The enzyme dipeptidyl peptidase-4 (DPP-4) rapidly degrades circulating GLP-1, which is why pharmaceutical versions are chemically modified to resist this breakdown and maintain therapeutic levels for extended periods

Reduces systemic inflammation and promotes regeneration

While some individuals report improvements in symptoms, research is still developing, and peptides should generally be viewed as part of a broader arthritis management strategy

Clinical studies have shown that patients using GLP-1 medications under medical supervision achieve significantly greater weight loss outcomes than those using lifestyle modifications alone