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Mao found that treating cancer cells with GPX4 inhibitors resulted in acute depletion of N-carbamyl-L-aspartate (C-ASP, a pyrimidine biosynthesis intermediate), accompanied by accumulation of uridine, which could be inhibited by fer-1, a ferroptosis inhibitor [18]

Excess cortisol production in circumstances such as Cushings disease or persistent stress can contribute to increased oxidative stress in the body

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GMC Number: 4362791 Ms Helena Antoniadou, MBBS, MD & Surg (Hons), FRCS (Eng)

This would have likely netted him another Nobel prize, but Watson and Crick beat him to it