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Aroda VR, Rosenstock J, Terauchi Y, Altuntas Y, Lalic NM, Morales Villegas EC, et al

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Confirming that liver mitochondrial biogenesis as a whole was not induced by IF, we found that activity of citrate synthase, a citric acid cycle enzyme and mitochondrial mass marker was equal in both groups (Fig

Thus, observed potent induction of ferroptosis, GPX4-dependent novel suppression of mTOR pathway and DNA damage repair response in preclinical in vitro model of TC supports GPX4 targeting for therapeutic benefit in advanced therapy-resistant thyroid cancers

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