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In some extreme cases, Magnetic Resonance Imaging - Proton Density Fat Fraction (MRI-PDFF) may not be possible for the largest individuals due to the patient size limitation of MRI systems

Another concern involves medication sterility and contamination

Published 2018 Oct 11

Possible cardiovascular symptoms include: Palpitations or a racing heart Increased blood pressure Chest discomfort Shortness of breath If you have a history of heart disease, uncontrolled high blood pressure, or arrhythmias, this combination is likely not safe for you

But ultimately, says Unitt, it will depend how they perform in the clinic