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We then sought to reproduce this finding by examining the effect of PAM genotype on response to once-weekly albiglutide therapy (30-50 mg) in the GSK-Harmony trial and once-weekly exenatide therapy (2 mg) in the EXSCEL study [32], [33]

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Notably, bone marrow lipid content is markedly increased in precursor MM states (MGUS and SMM) compared to healthy controls (Panaroni et al., 2022)

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