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The only other known strategy available to protect bacteria from iron intoxication is to efflux the metal from the cytoplasm, via ferrous ion transporters

Thornberry grew up in South Bend, Indiana and did a BSc in Natural Sciences at Muhlenberg College in Allentown, Pennsylvania, She joined Merck Research Laboratories as a biochemist in 1979 and became the director of enzymology in 1990

314 ISRIB restores eIF2B function and enhances gemcitabine-induced pancreatic cancer cell death